Axsome Therapeutics, Plug Power And Other Big Stocks Moving Higher On Wednesday

by | Dec 31, 2025 | General

U.S. stocks were lower, with the Dow Jones index falling more than 100 points on Wednesday.

Shares of Axsome Therapeutics, Inc. (NASDAQ:AXSM) rose sharply during Wednesday’s session after the company announced it intends to file a new drug application in January for AXS-12 after receiving feedback from the FDA. Additionally, the company announced the FDA granted Priority Review to AXS-05 for Alzheimer’s Agitation.

Axsome Therapeutics shares surged 16.1% to $172.90 on Wednesday.

Here are some other big stocks recording gains in today’s session.

  • Aimei Health Technology Co., Ltd (NASDAQ:AFJK) shares jumped 50.3% to $127.00.
  • Vanda Pharmaceuticals Inc. (NASDAQ:VNDA) gained 34.4% to $9.45 after the company announced it received FDA approval of NEREUS for the prevention of vomiting Induced by motion.
  • Jyong Biotech Ltd. (NASDAQ:MENS) gained 11.8% to $4.7107.
  • SELLAS Life Sciences Group, Inc. (NASDAQ:SLS) gained 7.5% to $3.5598.
  • Empresa Distribuidora y Comercializadora Norte Sociedad Anónima (NYSE:EDN) rose 6% to $31.93.
  • mF International Limited (NASDAQ:MFI) rose 4.8% to $19.46.
  • Plug Power Inc. (NASDAQ:PLUG) gained 4.1% to $2.0150. Clear Street analyst Tim Moore upgraded Plug Power from Hold to Buy and lowered the price target from $3.5 to $3.

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