U.S. stocks were mixed, with the Dow Jones index falling around 0.2% on Wednesday.

Shares of Monte Rosa Therapeutics Inc (NASDAQ:GLUE) rose sharply during Wednesday’s session after the company announced interim data from an ongoing Phase 1 clinical study evaluating MRT-8102.

Monte Rosa Therapeutics shares jumped 45.2% to $23.25 on Wednesday.

Here are some other big stocks recording gains in today’s session.

  • Ventyx Biosciences Inc (NASDAQ:VTYX) gained 37.5% to $13.82 following reports that Indianapolis-based Eli Lilly & Co. (NYSE:LLY) is in advanced talks to acquire the company for more than $1 billion, according to The Wall Street Journal.
  • Neumora Therapeutics Inc (NASDAQ:NMRA) rose 24.7% to $2.27.
  • Regencell Bioscience Holdings Ltd (NASDAQ:RGC) gained 21.1% to $40.00.
  • Erasca Inc (NASDAQ:ERAS) rose 17.1% to $4.25. Piper Sandler analyst Kelsey Goodwin initiated coverage on Erasca with an Overweight rating and announced a price target of $5.
  • Anywhere Real Estate Inc (NYSE:HOUS) gained 15.6% to $16.71.
  • AXT Inc (NASDAQ:AXTI) rose 13.8% to $22.96.
  • Immuneering Corp (NASDAQ:IMRX) gained 13.1% to $7.60.
  • Compass Therapeutics Inc. (NASDAQ:CMPX) gained 13.1% to $5.56.
  • MBX Biosciences Inc (NASDAQ:MBX) rose 11.2% to $31.90.
  • Rezolve AI PLC (NASDAQ:RZLV) rose 10.8% to $3.36.
  • United Microelectronics Corp (NYSE:UMC) gained 10.4% to $8.96 after the company reported December and full-year sales growth.
  • PBF Energy Inc (NYSE:PBF) rose 9.2% to $29.73.
  • Navan Inc (NASDAQ:NAVN) rose 8.3% to $18.42.
  • Ascentage Pharma Group International (NASDAQ:AAPG) gained 8.3% to $28.17. Ascentage Pharma announced IND clearance by the U.S. Food and Drug Administration for BTK Degrader APG-3288.
  • Intel Corp (NASDAQ:INTC) gained 6.4% to $42.60. Intel is ramping up its gaming ambitions by developing a new chip and platform specifically for handheld gaming devices.

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