U.S. stocks were higher, with the Dow Jones index gaining around 200 points on Wednesday.

Shares of Dynavax Technologies Corp (NASDAQ:DVAX) rose sharply during Wednesday’s session after Sanofi SA (NASDAQ:SNY) agreed to acquire the company for $15.50 per share in cash, reflecting a total equity value of approximately $2.2 billion.

The acquisition augments Sanofi’s presence in adult immunization.

Dynavax shares jumped 38.6% to $15.44 on Wednesday.

Here are some other big stocks recording gains in today’s session.

  • Omeros Corp (NASDAQ:OMER) shares jumped 66.8% to $14.60 after the FDA approved YARTEMLEA to treat hematopoietic stem cell transplant–associated thrombotic microangiopathy.
  • Edgewise Therapeutics Inc (NASDAQ:EWTX) gained 23.8% to $26.94. Edgewise Therapeutics on Wednesday shared updates from the ongoing CIRRUS-HCM Phase 2 trial of EDG-7500.
  • Agios Pharmaceuticals Inc (NASDAQ:AGIO) surged 17.9% to $29.00 after the company announced the FDA approved AQVESME for the treatment of anemia in adults with alpha- or beta-thalassemia. An exect announced AQVESME will be introduce at approximately $425,000 per patient per year.
  • Wheels Up Experience Inc (NYSE:UP) gained 14.8% to $0.73.
  • Travere Therapeutics Inc (NASDAQ:TVTX) gained 14.3% to $40.41.
  • Coincheck Group NV (NASDAQ:CNCK) surged 12.5% to $2.88.
  • Polestar Automotive Holding Uk Plc (NASDAQ:PSNY) jumped 11.8% to $16.92. Polestar Automotive recently announced a $300 million equity investment from Banco Bilbao Vizcaya Argentaria and Natixis.
  • CapsoVision Inc (NYSE:CV) gained 11.6% to $14.39.
  • X4 Pharmaceuticals Inc (NASDAQ:XFOR) gained 9.5% to $4.52.
  • Falcon’s Beyond Global Inc (NASDAQ:FBYD) jumped 9.4% to $18.35. Falcon’s Beyond Global recently announced filing of a $100 million mixed shelf offering.
  • BIOAGE Labs Inc (NASDAQ:BIOA) jumped 8.8% to $14.37.
  • Kodiak Sciences Inc (NASDAQ:KOD) gained 8.6% to $29.81.
  • UiPath Inc (NYSE:PATH) jumped 7.9% to $17.23 after it was announced that it will replace Synovus Financial in the S&P MidCap 400.
  • Immuneering Corp (NASDAQ:IMRX) rose 6.8% to $6.83. Immuneering announced that it would provide an update on 12-month overall survival from its ongoing Phase 2a clinical trial of atebimetinib + mGnP in first-line pancreatic cancer patients, on January 7, 2026.
  • Nike Inc (NYSE:NKE) gained 4.7% to $60.03 as investors weighed a notable insider purchase against ongoing concerns around tariffs, China demand, and a slower-than-expected turnaround.
  • Micron Technology Inc (NASDAQ:MU) gained 3.5% to $286.01.

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